Lenvatinib Impurity 71 CAS 2380197-89-5 (free base)
| CAS No. | 2380197-89-5 (free base) |
| Molecular Formula | C17H15N3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lenvatinib Impurity 71 (C17H15N3O3HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Lenvatinib Impurity 71 (CAS 2380197-89-5 (free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C17H15N3O3HCl and a molecular weight of 345.78 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lenvatinib Impurity 71 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H15N3O3 HCl |
| Molecular Weight | 345.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Lenvatinib Standards
- Lenvatinib Impurity 115 (CAS 106868-33-1)
- Lenvatinib Impurity 142 (CAS 1069122-99-1)
- Lenvatinib Impurity 48 (CAS 13021-02-8)
- Lenvatinib Impurity 71 (CAS 13066-95-0)
- Lenvatinib Impurity 93 (CAS 1378260-39-9)
- Lenvatinib Impurity N2 (CAS 13932-55-3)
- Lenvatinib Impurity 101 (CAS 1453-50-5)
- Lenvatinib Impurity 102 (CAS 15568-85-1)
Recommended Standards
- Ensifentrine Impurity 3 (CAS 3067475-18-4)
- Rimegepant Impurity 158 (CAS CATO-C4X-2487158)
- Cyromazine Impurity 1 (CAS 66215-24-5)
- (2R,3R)-2-(2-Chloro-phenyl)-1-ethyl-5-oxo-pyrrolidine-3-carboxylic acid (CAS 1175848-28-8)
- 2-Amino-5-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile (CAS 1805108-89-7)
- 5-Fluoro-2-methoxy-4-nitrobenzyl Alcohol (CAS 2006278-11-9)
- 4-(Sec-butyl)-5-(3-(morpholinosulfonyl)phenyl)-4h-1,2,4-triazole-3-thiol (CAS 522628-53-1)
- Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-2-(p-tolyl)-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 618072-59-6)
- 5-Benzyloxyindole-3-acetic Acid (CAS 4382-53-0)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com